• 커뮤니티
  • 세미나/콜로퀴움
세미나/콜로퀴움

PHYSICS/BK21 SEMINAR (08/07/14)

본문

"A flexible, multichannel microelectrode and its application to mouse EEG


연사: 최지현 박사[KIST 신경과학센터]

일시: 2008 년 7 월 14 일 10:30~11:30
장소: 물리학과 세미나실(공학3동 201호)

ABSTRACT:

Electroencephalography (EEG) of the mouse brain offers the advantage to monitor brain states in freely moving conditions under genetic or molecular manipulation. We present a novel, flexible, and biocompatible microfabricated electrode based on polyimide to record a multi-channel EEG from a mouse. Our microelectrode has 32 recording electrodes, including two ground electrodes. The connectors for the signal transmission are carefully affixed to the microelectrode. The overall weight of the microelectrode does not exceed 150 mg, including connectors. The implantation of the microelectrodes does not require invasive surgery and the mouse can be easily discharged from the wires when it is not being recorded. Simultaneous measurements with the microelectrode and a conventional screw electrode show that the microelectrode successfully collects the broad band EEG signals from the skull. A multi-channel mouse EEG is effective in monitoring spatiotemporal patterns of brain activity in a mouse. Statistical and dynamical parameters, such as entropy, correlation, and phase shifts were applied and the spatiotemporal patterns were shown for the first time in the intact mouse brain using the multi-channel mouse EEG.

문의처: 김승환(054-279-2085, swan@postech.ac.kr)
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